SCHEMBL24672934

SCHEMBL24672934

COC(=O)[C@H](O)CN1CCN(CC(O)c2ccccc2)CCN(C[C@@H](O)C(=O)OC)CC1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.62
ALDH1A1 P00352 1/20 0.62
GAA P10253 1/20 0.61
KMT2A Q03164 5/20 0.56
MEN1 O00255 4/20 0.56
OPRM1 P35372 1/20 0.56
OPRD1 P41143 1/20 0.56
PKM P14618 1/20 0.51
IGF1R P08069 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24673244 0.83 GAA (0.66) KDM4EALDH1A1GAAKMT2AMEN1
Acetic Acid SCHEMBL9325415 0.83 GAA (0.75) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL10746494 0.81 GAA (0.82) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL2796836 0.81 GAA (0.82) KDM4EALDH1A1GAAKMT2AMEN1
Propionic Acid SCHEMBL9328573 0.80 GAA (0.71) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL10640352 0.79 ALDH1A1 (0.95) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL352281 0.77 GAA (1.00) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL24672691 0.77 GAA (0.75) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL3976521 0.76 GAA (0.74) KDM4EALDH1A1GAAKMT2AMEN1
SCHEMBL14126889 0.75 GAA (0.59) KDM4EALDH1A1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed