⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23945766 | 0.88 | PIK3CD (0.35) | — | |
| SCHEMBL23806907 | 0.84 | PIK3CD (0.33) | — | |
| SCHEMBL24764633 | 0.81 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL24673267 | 0.80 | — | — | |
| SCHEMBL25883013 | 0.79 | DRD2 (0.36) | — | |
| SCHEMBL22861682 | 0.77 | GBA1 (0.36) | — | |
| SCHEMBL25888062 | 0.77 | PIK3CD (0.49) | — | |
| SCHEMBL178461 | 0.76 | PIK3CD (0.39) | — | |
| SCHEMBL21106038 | 0.76 | SIGMAR1 (0.36) | — | |
| SCHEMBL25468135 | 0.76 | GNAO1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340570-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. | 2022-10-27 | — | — | US | disclosed |