Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 10/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 1/20 | 0.41 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25145691 | 0.83 | LMNA (0.58) | LMNAHTR6SIGMAR1SLC6A2CHRM2 | |
| SCHEMBL28532123 | 0.80 | CYP2A13 (0.55) | LMNAMPOCXCR4MEN1KMT2A | |
| SCHEMBL8603826 | 0.78 | SLC6A2 (0.53) | LMNAHTR6SIGMAR1SLC6A2CXCR4 | |
| SCHEMBL24672239 | 0.75 | MPO (0.41) | HTR6MPOMEN1KMT2ATDP1 | |
| SCHEMBL31222568 | 0.74 | LMNA (0.54) | LMNAHTR6SIGMAR1MPOCXCR4 | |
| SCHEMBL14939663 | 0.74 | LMNA (0.67) | LMNAHTR6SIGMAR1SLC6A2MPO | |
| SCHEMBL31256898 | 0.74 | LMNA (0.62) | LMNAHTR6SIGMAR1MPOCXCR4 | |
| SCHEMBL1442446 | 0.74 | MPO (0.75) | LMNAHTR6SIGMAR1SLC6A2MPO | |
| SCHEMBL22285518 | 0.74 | LMNA (0.62) | LMNAHTR6SIGMAR1MPOCXCR4 | |
| SCHEMBL24672943 | 0.74 | SOS1 (0.46) | LMNAHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022204065-A1 | IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2022-09-29 | — | — | WO | disclosed |