SCHEMBL24672943

SCHEMBL24672943

O=S(=O)(O)c1ccc(O)c(CN2CCNCCNCC2)c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SOS1 Q07889 3/20 0.46
THRB P10828 1/20 0.45
CTSB P07858 1/20 0.45
LMNA P02545 2/20 0.44
PKM P14618 1/20 0.44
HTT P42858 1/20 0.44
TSHR P16473 2/20 0.43
GAA P10253 1/20 0.43
ACHE P22303 2/20 0.43
GFER P55789 1/20 0.42
BACE1 P56817 1/20 0.42
HTR6 P50406 2/20 0.41
ALDH1A1 P00352 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29942574 0.89 SOS1 (0.45) SOS1THRBCTSBLMNAPKM
SCHEMBL24672938 0.87 THRB (0.43) SOS1THRBCTSBLMNAPKM
SCHEMBL29942348 0.86 THRB (0.46) SOS1THRBCTSBLMNAPKM
SCHEMBL8718685 0.81 CTSB (0.70) CTSBLMNATSHRALDH1A1
SCHEMBL22773553 0.79 CTSB (0.71) THRBCTSBLMNATSHRGAA
SCHEMBL24672944 0.77 LMNA (0.52) THRBCTSBLMNAPKMHTT
SCHEMBL18753544 0.76 SMN1; SMN2 (0.50) SOS1LMNAHTTTSHRACHE
SCHEMBL18754006 0.76 ACHE (0.47) LMNATSHRACHEGFERBACE1
SCHEMBL22425608 0.76 LMNA (0.61) THRBLMNAPKMHTTTSHR
SCHEMBL6231104 0.76 ACHE (0.73) LMNATSHRACHEGFERBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed