SCHEMBL24673361

SCHEMBL24673361

COC(=O)[C@H](O)CN1CCN(C[C@@H](O)C(=O)OC)CCN(C[C@@H](N=O)C(=O)OC)CC1

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.32
PIK3CD O00329 1/20 0.32
PADI1 Q9ULC6 1/20 0.32
PADI4 Q9UM07 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KDM4E B2RXH2 3/20 0.30
ALDH1A1 P00352 3/20 0.30
HSD17B10 Q99714 1/20 0.30
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31758131 0.79 MEN1 (0.45) CYP2D6PADI1PADI4KDM4EALDH1A1
SCHEMBL840430 0.79 MEN1 (0.40) CYP2D6PADI1PADI4KDM4EALDH1A1
SCHEMBL840429 0.79 MEN1 (0.40) CYP2D6PADI1PADI4KDM4EALDH1A1
SCHEMBL31757749 0.75 USP2 (0.52) CYP2D6KDM4EALDH1A1HSD17B10USP2
SCHEMBL26421960 0.74 ALDH1A1 (0.38) CYP2D6PADI1PADI4KDM4EALDH1A1
SCHEMBL21806003 0.71 ABCB1 (0.45) CYP2D6KDM4EALDH1A1USP2MAPT
SCHEMBL24027253 0.71 ABCB1 (0.45) CYP2D6KDM4EALDH1A1USP2MAPT
SCHEMBL24672934 0.70 KDM4E (0.62) KDM4EALDH1A1
SCHEMBL22354590 0.66 ALDH1A1 (0.41) CYP2D6KDM4EALDH1A1HSD17B10MAPT
SCHEMBL28195478 0.64 CA1 (0.44) CYP3A4HSD17B10USP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022204065-A1 IRON(III) MACROCYCLIC COMPLEXES WITH MIXED HYROXYL PENDANTS AS MRI CONTRAST AGENTS THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-29 WO disclosed