SCHEMBL24673834

SCHEMBL24673834

Cc1cccc(-c2ccc(I)nc2)n1

nearest known ligand 0.54

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.54
CCR1 P32246 1/20 0.52
CCR8 P51685 1/20 0.52
GRM5 P41594 1/20 0.43
METAP2 P50579 1/20 0.42
TGFBR1 P36897 13/20 0.40
MAPK14 Q16539 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30146674 0.83 CYP2A6 (0.65) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL3421947 0.83 CYP2A6 (0.65) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL13051887 0.80 CCR1 (0.59) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL29457509 0.79 CYP2A6 (0.54) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL13680479 0.79 CYP2A6 (0.54) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL1743453 0.79 CYP2A6 (0.54) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL16835922 0.79 CYP2A6 (0.54) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL3422361 0.78 CCR1 (0.75) CYP2A6CCR1CCR8METAP2TGFBR1
SCHEMBL13680679 0.77 CCR1 (0.60) CYP2A6CCR1CCR8GRM5METAP2
SCHEMBL13680549 0.76 CYP2A6 (0.51) CYP2A6CCR1CCR8GRM5METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220384734-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220384734-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE MCOLN2, RER1, L1CAM CYP2A6 4327/4885CCR1 1154/4885CCR8 2315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.