Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24763856 | 1.00 | MEN1 (0.42) | MEN1KMT2ACXCR3HDAC6HDAC8 | |
| SCHEMBL24675006 | 0.91 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL30658110 | 0.91 | MEN1 (0.41) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL30729623 | 0.90 | CXCR3 (0.50) | MEN1KMT2ACXCR3HDAC6GPR119 | |
| SCHEMBL31491286 | 0.90 | CXCR3 (0.50) | MEN1KMT2ACXCR3HDAC6GPR119 | |
| SCHEMBL26958997 | 0.90 | CXCR3 (0.50) | MEN1KMT2ACXCR3HDAC6GPR119 | |
| SCHEMBL14465886 | 0.90 | CXCR3 (0.50) | MEN1KMT2ACXCR3HDAC6GPR119 | |
| SCHEMBL24764604 | 0.88 | GPR119 (0.42) | HDAC6HDAC8GPR119 | |
| SCHEMBL24675003 | 0.88 | HDAC6 (0.40) | MEN1KMT2AHDAC6HDAC8GPR119 | |
| SCHEMBL29274215 | 0.88 | HDAC6 (0.40) | MEN1KMT2AHDAC6HDAC8GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083274-A | Fused ring heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |