Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.42 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24763869 | 0.90 | GPR119 (0.40) | GPR119USP30HDAC8HDAC6IDO1 | |
| SCHEMBL24763856 | 0.88 | MEN1 (0.42) | GPR119HDAC8HDAC6 | |
| SCHEMBL24674717 | 0.88 | MEN1 (0.42) | GPR119HDAC8HDAC6 | |
| SCHEMBL24764607 | 0.88 | GPR119 (0.42) | GPR119 | |
| SCHEMBL34471700 | 0.87 | GPR119 (0.42) | GPR119TRPV3USP30IDO1TDO2 | |
| SCHEMBL31022332 | 0.87 | GPR119 (0.42) | GPR119TRPV3USP30IDO1TDO2 | |
| SCHEMBL31022118 | 0.87 | GPR119 (0.42) | GPR119TRPV3USP30IDO1TDO2 | |
| SCHEMBL31729445 | 0.85 | GPR119 (0.40) | GPR119TRPV3USP30HDAC8HDAC6 | |
| SCHEMBL31729058 | 0.83 | CYP3A4 (0.43) | GPR119TRPV3USP30 | |
| SCHEMBL14465886 | 0.82 | CXCR3 (0.50) | GPR119HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022184103-A1 | TRICYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 武汉誉祥医药科技有限公司 | 2022-09-09 | — | — | WO | disclosed |