Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4515539 | 0.81 | KMT2A (0.39) | ALDH1A1LMNAPLAUAGBL2KDM4E | |
| SCHEMBL4522170 | 0.75 | HPGD (0.47) | ALDH1A1PLAUAGBL2KDM4EMAPT | |
| SCHEMBL4522166 | 0.75 | HPGD (0.47) | ALDH1A1PLAUAGBL2KDM4EMAPT | |
| SCHEMBL28641181 | 0.74 | ALDH1A1 (0.47) | ALDH1A1PLAUAGBL2KDM4EMAPT | |
| SCHEMBL1498826 | 0.74 | ALDH1A1 (0.43) | ALDH1A1PLAUAGBL2KDM4ESMN1; SMN2 | |
| SCHEMBL5557029 | 0.74 | KMT2A (0.35) | ALDH1A1LMNAPLAUAGBL2KDM4E | |
| SCHEMBL30966491 | 0.72 | ALDH1A1 (0.42) | ALDH1A1LMNAPLAUAGBL2KDM4E | |
| SCHEMBL27229540 | 0.72 | ALDH1A1 (0.42) | ALDH1A1LMNAPLAUAGBL2KDM4E | |
| SCHEMBL10462276 | 0.72 | AGBL2 (0.51) | ALDH1A1LMNAPLAUAGBL2KDM4E | |
| SCHEMBL1971207 | 0.71 | ALDH1A1 (0.58) | ALDH1A1PLAUKDM4ESMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |