Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CBLB | Q13191 | 1/20 | 0.39 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675035 | 0.84 | ALDH1A1 (0.49) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL24675020 | 0.84 | ALDH1A1 (0.49) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL24675040 | 0.78 | TIPARP (0.40) | KMT2AMEN1KDM4EALDH1A1TIPARP | |
| SCHEMBL24675034 | 0.75 | ALDH1A1 (0.34) | KMT2AKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL24675022 | 0.75 | ALDH1A1 (0.34) | KMT2AKDM4EALDH1A1HPGDALOX15 | |
| SCHEMBL25045262 | 0.75 | CYP1A2 (0.52) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL29841734 | 0.73 | TIPARP (0.53) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL29841803 | 0.73 | TIPARP (0.53) | KMT2AMEN1KDM4EALDH1A1MAPT | |
| SCHEMBL24675031 | 0.73 | PIK3CA (0.35) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL26914999 | 0.73 | TIPARP (0.53) | KMT2AMEN1KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |