Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24675061 | 1.00 | HTR2A (0.39) | HTR2AHTR2CHTR2BKDM4EMEN1 | |
| SCHEMBL24675068 | 0.77 | HTR2A (0.40) | HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL7880701 | 0.71 | HTR2A (0.46) | HTR2AHTR2CHTR2BKDM4EKMT2A | |
| SCHEMBL24640800 | 0.71 | TIPARP (0.38) | — | |
| SCHEMBL24640054 | 0.71 | TIPARP (0.38) | — | |
| SCHEMBL24640017 | 0.71 | TIPARP (0.38) | — | |
| SCHEMBL1350944 | 0.69 | HTR2A (0.50) | HTR2AHTR2CHTR2BKDM4EMEN1 | |
| SCHEMBL24675035 | 0.69 | ALDH1A1 (0.49) | HTR2AHTR2CHTR2BKDM4EMEN1 | |
| SCHEMBL24675020 | 0.69 | ALDH1A1 (0.49) | HTR2AHTR2CHTR2BKDM4EMEN1 | |
| SCHEMBL24675039 | 0.69 | KMT2A (0.46) | HTR2AHTR2CHTR2BKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |