Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13098673 | 0.77 | TSHR (0.44) | OPRM1OPRL1CHRNB2CHRNB4CHRNA4 | |
| SCHEMBL14964832 | 0.75 | TSHR (0.59) | OPRM1OPRL1TSHR | |
| SCHEMBL2343051 | 0.75 | — | — | |
| SCHEMBL18214757 | 0.75 | — | — | |
| SCHEMBL30130345 | 0.73 | TSHR (0.41) | TSHR | |
| SCHEMBL14699658 | 0.73 | — | — | |
| SCHEMBL16144295 | 0.70 | OPRM1 (0.38) | OPRM1OPRL1KMT2ATSHR | |
| SCHEMBL20462570 | 0.70 | OPRM1 (0.38) | OPRM1OPRL1POLBTSHR | |
| SCHEMBL24674956 | 0.70 | OPRM1 (0.41) | OPRM1OPRL1TSHR | |
| SCHEMBL26401921 | 0.68 | KMT2A (0.44) | OPRM1OPRL1POLBKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022223022-A1 | FUSED-RING HETEROCYCLE DERIVATIVE AND MEDICAL APPLICATION THEREOF | 四川海思科制药有限公司 | 2022-10-27 | — | — | WO | disclosed |