SCHEMBL24675414

SCHEMBL24675414

c1ccc2c(c1)oc1ccc3c4ccccc4n(-c4ccc(-c5ccc(-n6c7ccccc7c7ccccc76)cc5)cc4)c3c12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
L3MBTL1 Q9Y468 3/20 0.43
ATM Q13315 1/20 0.43
HDAC4 P56524 1/20 0.37
ALDH1A1 P00352 5/20 0.34
SMN1; SMN2 Q16637 4/20 0.34
HPGD P15428 4/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
HSD17B10 Q99714 2/20 0.34
POLB P06746 1/20 0.34
MAPK1 P28482 1/20 0.34
DUSP3 P51452 1/20 0.34
PTPN5 P54829 1/20 0.34
PTPN11 Q06124 1/20 0.34
LMNA P02545 1/20 0.33
PTPN1 P18031 1/20 0.33
PLA2G2A P14555 2/20 0.33
PLA2G4A P47712 2/20 0.33
MAPT P10636 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24174744 1.00 KDM4E (0.43) KDM4EL3MBTL1ATMHDAC4ALDH1A1
SCHEMBL24676179 0.99 KDM4E (0.41) KDM4EL3MBTL1ATMHDAC4ALDH1A1
SCHEMBL24676321 0.99 KDM4E (0.41) KDM4EL3MBTL1ATMHDAC4ALDH1A1
SCHEMBL17246177 0.96 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1SMN1; SMN2
SCHEMBL24676095 0.94 KDM4E (0.44) KDM4EL3MBTL1ATMALDH1A1SMN1; SMN2
SCHEMBL24675488 0.92 ATM (0.41) KDM4EL3MBTL1ATMHDAC4ALDH1A1
SCHEMBL24676227 0.92 ATM (0.41) KDM4EL3MBTL1ATMHDAC4ALDH1A1
SCHEMBL24676170 0.92 ATM (0.41) KDM4EL3MBTL1ATMHDAC4ALDH1A1
SCHEMBL24676612 0.92 ATM (0.41) KDM4EL3MBTL1ATMHDAC4ALDH1A1
SCHEMBL24174202 0.92 KDM4E (0.38) KDM4EL3MBTL1ATMHDAC4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230309390-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-09-28 US disclosed
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-02 US disclosed
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2023-01-26 US disclosed
US-20220238815-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND, AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2022-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230027888-A1 ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE, ELECTRONIC DEVICE AND COMPOUND HTR1D, EHD1, HTR3D KDM4E 3361/4885L3MBTL1 1030/4885ATM 3140/4885
US-20230033529-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC DEVICE LEF1, L1CAM, RAP1A KDM4E 3096/4885L3MBTL1 173/4885ATM 2806/4885
US-20230309390-A1 ORGANIC LIGHT-EMITTING DEVICE L1CAM, EML4, OR10J3 KDM4E 2238/4885L3MBTL1 23/4885ATM 2243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.