Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.90 |
| ▸ | DRD2 | P14416 | 2/20 | 0.90 |
| ▸ | DRD4 | P21917 | 2/20 | 0.90 |
| ▸ | DRD3 | P35462 | 2/20 | 0.90 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7437721 | 0.95 | SLC6A3 (1.00) | SLC6A3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL16011858 | 0.85 | DRD2 (0.81) | SLC6A3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL16012062 | 0.82 | SLC6A3 (0.76) | SLC6A3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL16011800 | 0.82 | DRD2 (0.76) | SLC6A3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL16011798 | 0.72 | DRD2 (0.62) | SLC6A3DRD2DRD4DRD3 | |
| SCHEMBL16026371 | 0.72 | SLC6A3 (0.57) | SLC6A3DRD2DRD4DRD3SLC6A4 | |
| SCHEMBL14625327 | 0.72 | SIGMAR1 (0.79) | SLC6A3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL9973129 | 0.72 | SIGMAR1 (0.75) | SLC6A3DRD2DRD4DRD3KCNH2 | |
| SCHEMBL9973186 | 0.72 | SIGMAR1 (0.75) | DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL17339770 | 0.72 | KCNH2 (0.67) | SLC6A3DRD2DRD4DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964611-B1 | POTENT AND SELECTIVE INHIBITORS OF MONOAMINE TRANSPORTERS; METHOD OF MAKING; AND USE THEREOF | US HEALTH (US) | 2022-10-19 | — | — | EP | disclosed |