SCHEMBL24676542

SCHEMBL24676542

Cc1csc(C2CCCC2O[Si](C)(C)C(C)(C)C)n1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.30
RAB9A P51151 1/20 0.30
OGA O60502 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24676720 0.83
SCHEMBL24676715 0.75 RAB9A (0.39) SMN1; SMN2RAB9A
SCHEMBL24676724 0.73 OGA (0.34) SMN1; SMN2OGA
SCHEMBL24676716 0.70 RAB9A (0.39) SMN1; SMN2RAB9AOGA
SCHEMBL6400954 0.66 TACR1 (0.42)
SCHEMBL12043807 0.66 ADRA1A (0.33)
SCHEMBL31103363 0.65 PPM1D (0.34)
SCHEMBL31103366 0.65 PPM1D (0.34)
SCHEMBL12791651 0.64 OGA (0.44) SMN1; SMN2RAB9AOGA
SCHEMBL30741561 0.63 HCRTR1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022155941-A1 CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2022-07-28 WO disclosed