Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | OGA | O60502 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676877 | 0.76 | AR (0.33) | — | |
| SCHEMBL12791651 | 0.72 | OGA (0.44) | RAB9ASMN1; SMN2ALDH1A1NPC1NOS1 | |
| SCHEMBL6840373 | 0.71 | — | — | |
| SCHEMBL24676542 | 0.70 | SMN1; SMN2 (0.30) | RAB9ASMN1; SMN2OGA | |
| Ammonia Solution, Strong SCHEMBL27924535 | 0.70 | OGA (0.45) | RAB9ASMN1; SMN2ALDH1A1NPC1NOS1 | |
| SCHEMBL24677050 | 0.69 | NOS1 (0.38) | RAB9ASMN1; SMN2ALDH1A1NPC1NOS1 | |
| SCHEMBL29302278 | 0.68 | ALDH1A1 (0.48) | RAB9AALDH1A1NPC1L3MBTL1CNR2 | |
| SCHEMBL29302280 | 0.68 | GPR88 (0.43) | RAB9ASMN1; SMN2ALDH1A1NPC1NOS1 | |
| SCHEMBL10217223 | 0.67 | SSTR4 (0.39) | RAB9ASMN1; SMN2NOS1OGAHSD11B1 | |
| SCHEMBL9346290 | 0.67 | CHRNA7 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |