Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840373 | 0.79 | — | — | |
| Ammonia Solution, Strong SCHEMBL27924535 | 0.78 | OGA (0.45) | SMN1; SMN2NOS1OGARAB9ATRPV1 | |
| SCHEMBL12791651 | 0.76 | OGA (0.44) | SMN1; SMN2NOS1OGARAB9AHSD11B1 | |
| SCHEMBL24676000 | 0.74 | OGA (0.40) | SMN1; SMN2NOS1OGARAB9ATRPV1 | |
| SCHEMBL10217223 | 0.74 | SSTR4 (0.39) | SMN1; SMN2NOS1OGARAB9ATRPV1 | |
| SCHEMBL5291304 | 0.74 | RAB9A (0.46) | SMN1; SMN2NOS1OGARAB9AHSD11B1 | |
| SCHEMBL24677050 | 0.73 | NOS1 (0.38) | SMN1; SMN2NOS1OGARAB9ATRPV1 | |
| SCHEMBL20270748 | 0.73 | PSEN1 (0.36) | TRPV1 | |
| SCHEMBL3553310 | 0.72 | OGA (0.44) | SMN1; SMN2NOS1OGARAB9ATRPV1 | |
| SCHEMBL1042507 | 0.72 | HPGDS (0.47) | SMN1; SMN2NOS1OGARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |