SCHEMBL24676752

SCHEMBL24676752

CC(CO[Si](C)(C)C(C)(C)C)c1nc(C(F)(F)F)cs1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24675970 0.75 L3MBTL1 (0.36) MEN1KMT2A
SCHEMBL24676860 0.74 FFAR2 (0.36) MEN1KMT2A
SCHEMBL24676679 0.72 MEN1 (0.32) MEN1KMT2A
SCHEMBL9908284 0.71 CYP3A4 (0.38) MEN1KMT2A
SCHEMBL20113251 0.69 FFAR2 (0.35) MEN1KMT2A
SCHEMBL20738502 0.69 FFAR2 (0.35) MEN1KMT2A
SCHEMBL3338831 0.69 FFAR2 (0.35) MEN1KMT2A
SCHEMBL23528192 0.69 FFAR2 (0.35) MEN1KMT2A
SCHEMBL23528164 0.69 FFAR2 (0.38) MEN1KMT2A
SCHEMBL5662382 0.69 FFAR2 (0.35) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022155941-A1 CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2022-07-28 WO disclosed
WO-2022155941-A1 CDK2 INHIBITORS QILU REGOR THERAPEUTICS INC. (CN) 2022-07-28 WO disclosed