Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 20/20 | 0.55 |
| ▸ | CCNT1 | O60563 | 19/20 | 0.55 |
| ▸ | CDK2 | P24941 | 19/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 18/20 | 0.55 |
| ▸ | CDK1 | P06493 | 11/20 | 0.53 |
| ▸ | CDK7 | P50613 | 11/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 10/20 | 0.53 |
| ▸ | CCNH | P51946 | 10/20 | 0.53 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.53 |
| ▸ | CDK4 | P11802 | 3/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | CCND3 | P30281 | 2/20 | 0.42 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | WEE1 | P30291 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676825 | 0.86 | CCNA2 (0.43) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL24676829 | 0.81 | CCNT1 (0.43) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL24676488 | 0.78 | CDK2 (0.48) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL24676827 | 0.77 | CDK2 (0.42) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL29754870 | 0.75 | CDK2 (0.38) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL24675990 | 0.75 | CDK2 (0.38) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL24677046 | 0.75 | CCNT1 (0.34) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL24676010 | 0.74 | CCR6 (0.40) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL29754970 | 0.74 | CCR6 (0.40) | CDK9CCNT1CDK2CCNA2CDK1 | |
| SCHEMBL24676487 | 0.73 | TDO2 (0.41) | CDK9CCNT1CDK2CCNA2CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |