Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 4/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676993 | 0.77 | OPRM1 (0.36) | TACR1KCNH2CTSK | |
| SCHEMBL29754918 | 0.77 | OPRM1 (0.36) | TACR1KCNH2CTSK | |
| SCHEMBL24676757 | 0.64 | OPRM1 (0.36) | TACR1KCNH2CTSK | |
| SCHEMBL29754893 | 0.64 | OPRM1 (0.36) | TACR1KCNH2CTSK | |
| SCHEMBL25309788 | 0.63 | GAA (0.53) | KCNH2 | |
| SCHEMBL7458156 | 0.60 | CHRM2 (0.47) | KCNH2 | |
| SCHEMBL7455239 | 0.59 | CHRM2 (0.46) | KCNH2 | |
| SCHEMBL873248 | 0.59 | CHRM2 (0.46) | KCNH2 | |
| SCHEMBL6527496 | 0.58 | ADRA2A (0.45) | KCNH2LIPE | |
| SCHEMBL22369896 | 0.57 | IDH1 (0.33) | IDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |