Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 8/20 | 0.33 |
| ▸ | DRD4 | P21917 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29754918 | 1.00 | OPRM1 (0.36) | OPRM1OPRL1CTSLCTSBCTSK | |
| SCHEMBL29754893 | 0.87 | OPRM1 (0.36) | OPRM1OPRL1CTSLCTSBCTSK | |
| SCHEMBL24676757 | 0.87 | OPRM1 (0.36) | OPRM1OPRL1CTSLCTSBCTSK | |
| SCHEMBL24676864 | 0.77 | TACR1 (0.33) | CTSKTACR1KCNH2 | |
| SCHEMBL24676758 | 0.76 | TRPV1 (0.37) | OPRM1OPRL1CTSLCTSBCTSK | |
| SCHEMBL25025800 | 0.75 | P2RX7 (0.38) | OPRM1OPRL1CTSLCTSBCTSK | |
| SCHEMBL20284996 | 0.72 | OPRM1 (0.51) | OPRM1OPRL1CTSLCTSBCTSK | |
| SCHEMBL29754940 | 0.70 | OPRM1 (0.32) | OPRM1OPRL1 | |
| SCHEMBL3830852 | 0.70 | CTSL (0.49) | OPRM1OPRL1CTSLCTSBCTSK | |
| SCHEMBL446380 | 0.68 | CTSL (0.39) | OPRM1OPRL1CTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |