SCHEMBL24676923

SCHEMBL24676923

Cc1cccc(-c2cccc(B3c4ccccc4Oc4ccccc43)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.38
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
TSHR P16473 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ALDH1A1 P00352 4/20 0.36
KMT2A Q03164 1/20 0.36
ENPP3 O14638 2/20 0.35
PTPN5 P54829 1/20 0.34
MAPK1 P28482 3/20 0.33
TP53 P04637 2/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
MAP4K4 O95819 1/20 0.33
ACHE P22303 1/20 0.33
MAOB P27338 1/20 0.33
RECQL P46063 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24367706 0.90 ACHE (0.38) HPGDRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL24676929 0.87 MAOA (0.35) ALDH1A1KMT2AMAPK1KDM4EL3MBTL1
SCHEMBL24631900 0.83 HPGD (0.37) HPGDRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL24677087 0.81 RXRA (0.34) HPGDRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL24676988 0.81
SCHEMBL26724104 0.78
SCHEMBL24632025 0.75 NR3C2 (0.36) HPGDRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL26194143 0.74 P2RX4 (0.38) HPGDTSHRACHEMAOBTDP1
SCHEMBL26794213 0.73 AHR (0.33)
SCHEMBL21965189 0.73 AHR (0.37) MAPK1MAOBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP HPGD 1116/4885RAB9A 1429/4885NPC1 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.