Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24676049 | 0.74 | TRPV1 (0.39) | — | |
| SCHEMBL20789242 | 0.71 | BACE1 (0.35) | CHRM2CHRM1CHRM3KIF11 | |
| SCHEMBL20789244 | 0.71 | BACE1 (0.35) | CHRM2CHRM1CHRM3KIF11 | |
| SCHEMBL498175 | 0.71 | — | — | |
| SCHEMBL24676042 | 0.71 | NOS3 (0.32) | CHRM2CHRM1CHRM3 | |
| SCHEMBL30951469 | 0.69 | NUDT1 (0.35) | — | |
| SCHEMBL3982871 | 0.68 | HRH3 (0.46) | — | |
| SCHEMBL3982869 | 0.68 | HRH3 (0.46) | — | |
| SCHEMBL24676709 | 0.67 | DRD4 (0.36) | — | |
| SCHEMBL29599566 | 0.67 | PPM1D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |