Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25164697 | 0.80 | TRPV1 (0.41) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL24677043 | 0.76 | TRPV1 (0.35) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL24677053 | 0.75 | NR1H2 (0.40) | HCRTR2KDM4EIDH1 | |
| SCHEMBL20271181 | 0.75 | PSEN1 (0.39) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20270106 | 0.75 | TRPV1 (0.39) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20270748 | 0.75 | PSEN1 (0.36) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL21314668 | 0.75 | TRPV1 (0.39) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29754965 | 0.74 | TRPV1 (0.37) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29754920 | 0.74 | TRPV1 (0.35) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL18711434 | 0.72 | SPR (0.47) | TRPV1SPRIDH1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |