Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | LCAT | P04180 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12540285 | 0.84 | TRPV1 (0.41) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL24677043 | 0.83 | TRPV1 (0.35) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL20270106 | 0.82 | TRPV1 (0.39) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL20271181 | 0.82 | PSEN1 (0.39) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL20270748 | 0.82 | PSEN1 (0.36) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL21314668 | 0.82 | TRPV1 (0.39) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL24676081 | 0.81 | IDH1 (0.36) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL24677051 | 0.80 | LMNA (0.36) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL24676492 | 0.80 | TRPV1 (0.36) | TRPV1IDH1PSEN1PSEN2APH1B | |
| SCHEMBL12364538 | 0.80 | ATAD2 (0.44) | LMNAHCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064343-A1 | SMALL MOLECULE MODULATORS OF GLUCOCEREBROSIDASE ACTIVITY AND USES THEREOF | VANQUA BIO, INC. (US) | 2023-04-20 | — | — | WO | disclosed |