Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9947823 | 0.83 | HSD11B1 (0.44) | NR1H2GPR119KDM4EMAPTUSP30 | |
| SCHEMBL16717787 | 0.82 | GPR119 (0.40) | NR1H2RORCGPR119KDM4EMAPT | |
| SCHEMBL22812076 | 0.82 | GPR119 (0.40) | NR1H2RORCGPR119KDM4EMAPT | |
| SCHEMBL18765254 | 0.81 | GPR119 (0.39) | NR1H2RORCGPR119KDM4EMAPT | |
| SCHEMBL1118383 | 0.79 | GPR119 (0.46) | NR1H2GPR119KDM4EMAPTNAMPT | |
| SCHEMBL18764918 | 0.76 | NR1H2 (0.51) | NR1H2GPR119MAPT | |
| SCHEMBL24677051 | 0.75 | LMNA (0.36) | KDM4EHCRTR2IDH1 | |
| SCHEMBL4573137 | 0.75 | CTSB (0.46) | GPR119MAPTHDAC4 | |
| SCHEMBL23702818 | 0.75 | PIK3CD (0.47) | USP30 | |
| SCHEMBL23708849 | 0.75 | PIK3CD (0.47) | USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022155941-A1 | CDK2 INHIBITORS | QILU REGOR THERAPEUTICS INC. (CN) | 2022-07-28 | — | — | WO | disclosed |