SCHEMBL24677095

SCHEMBL24677095

Ic1ccc2c(c1)c1ccccc1n2-c1nccc2c1oc1ccccc12

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 3/20 0.34
▸ TSHR P16473 3/20 0.34
▸ LMNA P02545 2/20 0.34
▸ NPC1 O15118 2/20 0.33
▸ DRD4 P21917 1/20 0.33
▸ AHR P35869 1/20 0.31
▸ MEN1 O00255 2/20 0.31
▸ HTT P42858 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ USP2 O75604 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ ALOX5 P09917 2/20 0.31
▸ KDM4E B2RXH2 2/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ CDK2 P24941 1/20 0.30
▸ GSK3B P49841 1/20 0.30
▸ LIMK1 P53667 1/20 0.30
▸ PRKDC P78527 1/20 0.30
▸ HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24367811 0.88 MAPT (0.40) MAPTTSHRLMNANPC1DRD4
SCHEMBL11885218 0.88 ALOX5 (0.36) MAPTTSHRLMNANPC1DRD4
SCHEMBL10451079 0.86 KDM4E (0.35) MAPTTSHRLMNANPC1DRD4
SCHEMBL23772974 0.85 MAPT (0.34) MAPTTSHRLMNANPC1DRD4
SCHEMBL22373702 0.85 TSHR (0.37) MAPTTSHRLMNANPC1DRD4
SCHEMBL25885740 0.83 — —
SCHEMBL11885008 0.82 KDM4E (0.41) MAPTTSHRLMNANPC1DRD4
SCHEMBL13245640 0.81 KDM4E (0.35) MAPTTSHRLMNANPC1MEN1
SCHEMBL13245641 0.81 KDM4E (0.35) MAPTTSHRLMNANPC1MEN1
SCHEMBL11884991 0.81 ALOX5 (0.35) MAPTTSHRLMNANPC1DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4282863-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-11-29 — — EP disclosed
US-20230287017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 — — US disclosed
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287017-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, NONO MAPT 1038/4885TSHR 1547/4885LMNA 4558/4885
US-20220336747-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP MAPT 898/4885TSHR 3460/4885LMNA 2908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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