Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2467754 | 1.00 | MAPT (0.53) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11697084 | 0.92 | BACE1 (0.54) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11697081 | 0.92 | BACE1 (0.54) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9744309 | 0.88 | IDH1 (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9744306 | 0.88 | IDH1 (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL24075808 | 0.85 | MAPT (0.52) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11697629 | 0.83 | ESR1 (0.50) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11697621 | 0.83 | ESR1 (0.50) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11790930 | 0.80 | ALDH1A1 (0.66) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL11579939 | 0.80 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8519197-B2 | Synthesis of magnolol and its analogue compounds | COLGATE-PALMOLIVE COMPANY (US) | 2013-08-27 | — | — | US | disclosed |
| US-8519197-B2 | Synthesis of magnolol and its analogue compounds | COLGATE-PALMOLIVE COMPANY (US) | 2013-08-27 | — | — | US | disclosed |
| US-8519197-B2 | Synthesis of magnolol and its analogue compounds | COLGATE-PALMOLIVE COMPANY (US) | 2013-08-27 | — | — | US | disclosed |
| US-20120302647-A1 | SYNTHESIS OF MAGNOLOL AND ITS ANALOGUE COMPOUNDS | INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY (IN) | 2012-11-29 | — | — | US | disclosed |
| US-20120302647-A1 | SYNTHESIS OF MAGNOLOL AND ITS ANALOGUE COMPOUNDS | INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY (IN) | 2012-11-29 | — | — | US | disclosed |
| US-20120302647-A1 | SYNTHESIS OF MAGNOLOL AND ITS ANALOGUE COMPOUNDS | INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY (IN) | 2012-11-29 | — | — | US | disclosed |
| WO-2011106003-A1 | SYNTHESIS OF MAGNOLOL AND ITS ANALOGUE COMPOUNDS | COLGATE-PALMOLIVE COMPANY (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302647-A1 | SYNTHESIS OF MAGNOLOL AND ITS ANALOGUE COMPOUNDS | CYP11B2, CYP11B1, ADRB2 | MAPT 1880/4885KDM4E 1987/4885ALDH1A1 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.