Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.52 |
| ▸ | ADH1C | P00326 | 2/20 | 0.52 |
| ▸ | ADH1A | P07327 | 2/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17503936 | 1.00 | ADH1B (0.52) | ADH1BADH1CADH1AADH7ADRB2 | |
| SCHEMBL3307130 | 0.85 | ADH1B (0.55) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL8763196 | 0.79 | ADH1B (0.76) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL6720044 | 0.78 | ADH1B (0.52) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL11304055 | 0.77 | ADH1B (0.55) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL17503962 | 0.74 | ADH1B (0.61) | ADH1BADH1CADH1AADH7 | |
| SCHEMBL43651 | 0.74 | ADH1B (0.61) | ADH1BADH1CADH1AADH7ITGB1 | |
| SCHEMBL4633463 | 0.74 | ADH1B (0.61) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL31566 | 0.74 | ADH1B (0.61) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL8763263 | 0.73 | ADH1B (0.67) | ADH1BADH1CADH1AADH7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022178030-A1 | TRPM8 AGONISTS AS COOLING AGENTS AND FOR THE TREATMENT OF DISEASE | Concentric Analgesics, Inc. (US) | 2022-08-25 | — | — | WO | disclosed |