Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3307130 | 0.81 | ADH1B (0.55) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL8763196 | 0.79 | ADH1B (0.76) | ADH1BADH1CADH1AADH7MEN1 | |
| SCHEMBL4633463 | 0.78 | ADH1B (0.61) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL24677567 | 0.78 | ADH1B (0.52) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL17503936 | 0.78 | ADH1B (0.52) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL28330193 | 0.76 | ESR1 (0.47) | HDAC8HDAC6ESR1ESR2ADRA2A | |
| SCHEMBL13178691 | 0.76 | ESR1 (0.47) | HDAC8HDAC6ESR1ESR2ADRA2A | |
| SCHEMBL31566 | 0.74 | ADH1B (0.61) | ADH1BADH1CADH1AADH7L3MBTL1 | |
| SCHEMBL8763263 | 0.73 | ADH1B (0.67) | ADH1BADH1CADH1AADH7ESR1 | |
| SCHEMBL11304055 | 0.73 | ADH1B (0.55) | ADH1BADH1CADH1AADH7ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | claimed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | claimed |