⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189945 | 0.76 | — | — | |
| SCHEMBL27098380 | 0.76 | — | — | |
| SCHEMBL8164049 | 0.76 | — | — | |
| SCHEMBL12495760 | 0.74 | — | — | |
| SCHEMBL24677737 | 0.74 | ELANE (0.31) | — | |
| SCHEMBL15775212 | 0.74 | BRD4 (0.36) | — | |
| SCHEMBL10832823 | 0.74 | PDK1 (0.34) | — | |
| SCHEMBL23834464 | 0.74 | HTR1A (0.30) | — | |
| Hydrochloric Acid SCHEMBL18037794 | 0.72 | — | — | |
| SCHEMBL783284 | 0.71 | OPRM1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4444300-A2 | INHIBITORS OF MENIN-MLL INTERACTION | Bala Therapeutics, Inc. (US) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| WO-2022188819-A1 | SOS1 PROTEOLYSIS MODULATOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-09-15 | — | — | WO | disclosed |