Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aptocaine SCHEMBL29417821 | 1.00 | ATM (0.71) | ATMALDH1A1SMN1; SMN2NPC1MAPT | |
| Aptocaine SCHEMBL246792 | 1.00 | ATM (0.71) | ATMALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL18485508 | 0.83 | ATM (1.00) | ATMALDH1A1SMN1; SMN2NPC1NPSR1 | |
| Lidocaine SCHEMBL15568985 | 0.82 | ATM (0.62) | ATMALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL18486453 | 0.82 | ATM (0.97) | ATMALDH1A1SMN1; SMN2NPC1NPSR1 | |
| SCHEMBL22746436 | 0.82 | ATM (0.97) | ATMALDH1A1SMN1; SMN2NPC1NPSR1 | |
| SCHEMBL11006712 | 0.80 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2NPC1MAPTKMT2A | |
| SCHEMBL3012625 | 0.78 | ALDH1A1 (0.66) | ATMALDH1A1SMN1; SMN2NPC1MAPT | |
| SCHEMBL5186841 | 0.77 | MDM4 (0.67) | ALDH1A1NPC1MAPTL3MBTL1PGR | |
| SCHEMBL6351292 | 0.75 | NPC1 (0.62) | ALDH1A1NPC1MAPTPGRSCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 194 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096452-A1 | LOCAL ANESTHETIC FOR THE TREATMENT OF NEUROLOGICAL SYMPTOMS RESULTING FROM BRAIN DYSFUNCTIONS | ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) | 2022-03-31 | — | — | US | claimed |
| EP-3914246-A1 | LOCAL ANESTHETIC FOR THE TREATMENT OF NEUROLOGICAL SYMPTOMS RESULTING FROM BRAIN DYSFUNCTIONS | ICM (Institut du Cerveau et de la Moelle Épinière) (FR) | 2021-12-01 | — | — | EP | claimed |
| WO-2020152212-A1 | LOCAL ANESTHETIC FOR THE TREATMENT OF NEUROLOGICAL SYMPTOMS RESULTING FROM BRAIN DYSFUNCTIONS | ICM (INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE) (FR) | 2020-07-30 | — | — | WO | claimed |
| WO-2020043834-A1 | POLYURETHANE SHEET | STICHTING KATHOLIEKE UNIVERSITEIT (NL) | 2020-03-05 | — | — | WO | claimed |
| US-20180264169-A1 | COMPOSITIONS COMPRISING AT LEAST ONE POLYOL AND AT LEAST ONE ANESTHETIC | LABORATOIRES VIVACY (FR) | 2018-09-20 | — | — | US | claimed |
| US-10004824-B2 | Compositions comprising at least one polyol and at least one anesthetic | LABORATOIRES VIVACY (FR) | 2018-06-26 | — | — | US | claimed |
| EP-3294355-A1 | COMPOSITIONS COMPRISING AT LEAST ONE POLYOL AND AT LEAST ONE ANAESTHETIC | Laboratoires Vivacy (FR) | 2018-03-21 | — | — | EP | claimed |
| CN-107735084-A | Composition comprising at least one polyalcohol and at least one anesthetic | 实验室维维西公司 | 2018-02-23 | — | — | CN | claimed |
| US-20160331865-A1 | Compositions comprising at least one polyol and at least one anesthetic | LABORATOIRES VIVACY (FR) | 2016-11-17 | — | — | US | claimed |
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| EP-1931416-A2 | IONTOPHORESIS METHOD AND APPARATUS FOR SYSTEMIC DELIVERY OF ACTIVE AGENTS | TTI ELLEBEAU, INC. (JP) | 2008-06-18 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| US-20070093788-A1 | Iontophoresis method and apparatus for systemic delivery of active agents | TRANSCUTANEOUS TECHNOLOGIES INC. (JP) | 2007-04-26 | — | — | US | claimed |
| WO-2007041300-A2 | IONTOPHORESIS METHOD AND APPARATUS FOR SYSTEMIC DELIVERY OF ACTIVE AGENTS | TTI ELLEBEAU, INC. (JP) | 2007-04-12 | — | — | WO | claimed |
| US-6071959-A | FOR RELIEVING PAIN OF LOWER GASTROINTESTINAL TRACT BY RECTAL OR ORAL ADMINISTRATION OF A COMPLEX OF AMIDE-TYPE LOCAL ANAESTHETIC AND POLYACRYLATE WITH CARRIER, DILUENT AND/OR EXCIPIENT | RHODES JOHN (GB) | 2000-06-06 | — | — | US | claimed |
| EP-0914106-A1 | PHARMACEUTICAL PRODUCTS CONTAINING A COMPLEX OF AN AMIDE-TYPE LOCAL ANESTHETIC AND A POLYACRYLATE | RHODES, John (GB) | 1999-05-12 | — | — | EP | claimed |
| WO-1997044021-A1 | PHARMACEUTICAL PRODUCTS CONTAINING A COMPLEX OF AN AMIDE-TYPE LOCAL ANESTHETIC AND A POLYACRYLATE | RHODES JOHN (GB) | 1997-11-27 | — | — | WO | claimed |
| US-4557934-A | ALONG WITH A DIOL PYRROLIDONE OR AN AZACYCLOPENTAN-2-ONE | THE PROCTER & GAMBLE COMPANY (US) | 1985-12-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220096452-A1 | LOCAL ANESTHETIC FOR THE TREATMENT OF NEUROLOGICAL SYMPTOMS RESULTING FROM BRAIN DYSFUNCTIONS | FABP7, ALB, SLC1A2 | ATM 588/4885ALDH1A1 1989/4885SMN1; SMN2 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.