Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942761 | 0.81 | — | — | |
| SCHEMBL15349037 | 0.79 | FBP1 (0.31) | — | |
| SCHEMBL24116011 | 0.73 | NLRP3 (0.33) | — | |
| SCHEMBL5543974 | 0.73 | — | — | |
| SCHEMBL15437081 | 0.71 | HSD17B10 (0.36) | HSD17B10KDM4EALDH1A1 | |
| SCHEMBL104766 | 0.70 | COMT (0.32) | HSD17B10ALDH1A1 | |
| SCHEMBL18002772 | 0.70 | — | — | |
| SCHEMBL24599440 | 0.69 | RORC (0.33) | KDM4EALDH1A1 | |
| SCHEMBL11292151 | 0.69 | NPC1 (0.30) | HSD17B10ALDH1A1 | |
| SCHEMBL13145329 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022235575-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION (US) | 2022-11-10 | — | — | WO | disclosed |