Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2639145 | 0.85 | ADRA2A (0.45) | CYP1A2CYP1A1CYP1B1CYP2D6ADRA2A | |
| SCHEMBL16957658 | 0.85 | ERN1 (0.41) | CYP1A2CYP1A1CYP1B1CYP2D6ADRA2A | |
| SCHEMBL7304531 | 0.81 | ALDH1A1 (0.59) | CYP1A2CYP1A1CYP1B1CYP2D6ADRA2A | |
| SCHEMBL9065566 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP1A1CYP1B1CYP2D6MEN1 | |
| SCHEMBL30567454 | 0.78 | CYP1A2 (0.52) | CYP1A2CYP1A1CYP1B1CYP2D6MEN1 | |
| SCHEMBL16951297 | 0.76 | CYP2D6 (0.41) | CYP1A2CYP1A1CYP1B1CYP2D6ADRA2A | |
| SCHEMBL10304814 | 0.76 | CYP2D6 (0.50) | CYP1A2CYP2D6ADRA2AADRA1AMEN1 | |
| SCHEMBL5026272 | 0.75 | CYP1A2 (0.50) | CYP1A2CYP1A1CYP1B1CYP2D6MEN1 | |
| SCHEMBL25893482 | 0.75 | KDM4E (0.45) | ALDH1A1NFE2L2KDM4ESMN1; SMN2MAPT | |
| 4-Vinylphenol SCHEMBL5900822 | 0.75 | CYP1A1 (0.43) | CYP1A2CYP1A1CYP1B1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230143250-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARMACEUTICALS, INC. | 2023-05-11 | — | — | US | disclosed |
| EP-1395622-B1 | ARBORESCENT THERMOPLASTIC ELASTOMERS AND PRODUCTS THEREFROM | AUSTIN VENTURE PARTNERS LLC (US) | 2011-10-05 | — | — | EP | disclosed |
| US-6747098-B2 | A BRANCHED BLOCK COPOLYMER COMPRISING A LOW GLASS TRANSITION TEMPERATURE SOFT SEGMENTS AND RIGID SEGMENTS WITH A HIGH TRANSITION TEMPERATURE OR CRYSTALLINE MELTING POINT; NON-BIODEGRADABLE IMPLANTABLE PROSTHESUS | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2004-06-08 | — | — | US | disclosed |
| EP-1395622-A1 | ARBORESCENT THERMOPLASTIC ELASTOMERS AND PRODUCTS THEREFROM | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2004-03-10 | — | — | EP | disclosed |
| US-20030065098-A1 | Arborescent thermoplastic elastomers and products therefrom | AUSTIN VENTURE PARTNERS, LLC | 2003-04-03 | — | — | US | disclosed |
| WO-2002096967-A1 | ARBORESCENT THERMOPLASTIC ELASTOMERS AND PRODUCTS THEREFROM | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230143250-A1 | 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS AND METHODS OF USE THEREOF | HSD17B1, HSD17B13, HSD17B3 | CYP1A2 83/4885CYP1A1 224/4885CYP1B1 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.