SCHEMBL24680322

SCHEMBL24680322

COC(C)C12CCCN1CCC2

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24681030 0.80
SCHEMBL25649720 0.77 LMNA (0.32)
SCHEMBL24858503 0.77
SCHEMBL24176427 0.73 SLC6A9 (0.38) SLC6A9
SCHEMBL26711005 0.71 SLC6A9 (0.40) SLC6A9
SCHEMBL7349132 0.71
SCHEMBL23053916 0.71
SCHEMBL23043769 0.70 PRKCA (0.31)
SCHEMBL24176429 0.70 SLC6A9 (0.39) SLC6A9
SCHEMBL26745951 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022188729-A1 FUSED RING DERIVATIVES USEFUL AS KRAS G12D INHIBITORS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-09-15 WO disclosed