Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | F11 | P03951 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | CSK | P41240 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL649272 | 0.82 | IDO1 (0.44) | — | |
| SCHEMBL12663141 | 0.79 | LPL (0.43) | LPLLIPGCA2CA1F11 | |
| SCHEMBL11979782 | 0.79 | TAAR1 (0.50) | CA2CA1 | |
| SCHEMBL12936619 | 0.77 | LTA4H (0.39) | CA2CA1TSHR | |
| SCHEMBL104085 | 0.77 | LPL (0.58) | LPLLIPGCA2CA1F11 | |
| SCHEMBL1337524 | 0.76 | IDO1 (0.41) | — | |
| SCHEMBL8750390 | 0.74 | TDP1 (0.40) | LPLLIPGCA2TSHR | |
| SCHEMBL12134040 | 0.74 | ACACB (0.39) | — | |
| SCHEMBL407132 | 0.74 | AGXT (0.54) | CA2CA1 | |
| SCHEMBL13978537 | 0.73 | LPL (0.59) | LPLLIPGCA2CA1F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188729-A1 | FUSED RING DERIVATIVES USEFUL AS KRAS G12D INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |