Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2802710 | 0.88 | AOC3 (0.46) | DHFRHSD17B2 | |
| SCHEMBL13859211 | 0.87 | DHFR (0.45) | DHFRMEN1KMT2APDE4APDE4B | |
| SCHEMBL22122696 | 0.85 | KMT2A (0.47) | DHFRMEN1KMT2ANPC1POLB | |
| SCHEMBL2683955 | 0.85 | KMT2A (0.47) | DHFRMEN1KMT2ANPC1POLB | |
| SCHEMBL2466860 | 0.84 | DHFR (0.39) | DHFRIDO1 | |
| SCHEMBL23572596 | 0.82 | APP (0.49) | DHFRMEN1KMT2ANPC1POLB | |
| SCHEMBL2685285 | 0.82 | APP (0.49) | DHFRMEN1KMT2ANPC1POLB | |
| SCHEMBL2519799 | 0.77 | TSHR (0.52) | KMT2APOLBIDO1CYP1A2CYP3A4 | |
| SCHEMBL2801832 | 0.77 | TSHR (0.52) | KMT2APOLBIDO1CYP1A2CYP3A4 | |
| SCHEMBL17845069 | 0.77 | APP (0.48) | KMT2APOLBIDO1HSD17B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119778-A2 | METHOD FOR IN-SITU FORMATION OF METATHESIS CATALYSTS | SCHRODI YANN (US) | 2011-09-29 | — | — | WO | disclosed |