Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29799952 | 1.00 | TSPO (0.42) | TSPOPDK1ALDH1A1DYRK1AMEN1 | |
| SCHEMBL24682174 | 0.91 | TSPO (0.44) | TSPOPDK1DYRK1AMEN1KMT2A | |
| SCHEMBL29799804 | 0.91 | TSPO (0.44) | TSPOPDK1DYRK1AMEN1KMT2A | |
| SCHEMBL29800041 | 0.87 | MAPT (0.43) | TSPOPDK1ALDH1A1DYRK1AMEN1 | |
| SCHEMBL24682178 | 0.87 | MAPT (0.43) | TSPOPDK1ALDH1A1DYRK1AMEN1 | |
| SCHEMBL29799815 | 0.87 | PDK1 (0.45) | TSPOPDK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24682202 | 0.87 | PDK1 (0.45) | TSPOPDK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24683240 | 0.85 | PDK1 (0.41) | TSPOPDK1MEN1KMT2AL3MBTL1 | |
| SCHEMBL24683154 | 0.85 | LMNA (0.45) | TSPOPDK1ALDH1A1MEN1KMT2A | |
| SCHEMBL29800048 | 0.85 | LMNA (0.45) | TSPOPDK1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |