Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2673060 | 0.92 | HDAC1 (0.58) | METMEN1KMT2ATP53MAPT | |
| SCHEMBL2672593 | 0.91 | ALDH1A1 (0.59) | METMEN1KMT2ATP53MAPT | |
| Hydrochloric Acid SCHEMBL2673128 | 0.90 | ALDH1A1 (0.58) | METMEN1KMT2ATP53MAPT | |
| SCHEMBL2464489 | 0.87 | MET (0.79) | METHDAC1 | |
| SCHEMBL2469377 | 0.86 | MET (0.66) | METMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2672902 | 0.86 | MET (0.78) | METHDAC1 | |
| SCHEMBL3117528 | 0.86 | MET (0.59) | METMEN1KMT2ATP53MAPT | |
| SCHEMBL2470219 | 0.85 | MET (0.62) | METMEN1KMT2AMAPTHDAC1 | |
| SCHEMBL3111915 | 0.85 | MET (0.58) | METMEN1KMT2ATP53MAPT | |
| SCHEMBL2469567 | 0.85 | MET (0.67) | METMEN1KMT2AHDAC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960370-B1 | PYRIDIAZINONE DERIVATIVES FOR TUMOUR TREATMENT | MERCK PATENT GMBH (DE) | 2011-10-05 | — | — | EP | claimed |