Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29800148 | 1.00 | MAOB (0.40) | MAOBMAPTSNCAHDAC3HDAC1 | |
| SCHEMBL24683240 | 0.92 | PDK1 (0.41) | MAOBMAPTSNCAHDAC3HDAC1 | |
| SCHEMBL29799894 | 0.92 | PDK1 (0.41) | MAOBMAPTSNCAHDAC3HDAC1 | |
| SCHEMBL29799815 | 0.88 | PDK1 (0.45) | MAOBMAPTSNCATSPOPDK1 | |
| SCHEMBL24682202 | 0.88 | PDK1 (0.45) | MAOBMAPTSNCATSPOPDK1 | |
| SCHEMBL24682174 | 0.85 | TSPO (0.44) | TSPOPDK1 | |
| SCHEMBL29799804 | 0.85 | TSPO (0.44) | TSPOPDK1 | |
| SCHEMBL24682178 | 0.83 | MAPT (0.43) | MAPTTSPOPDK1 | |
| SCHEMBL29800041 | 0.83 | MAPT (0.43) | MAPTTSPOPDK1 | |
| SCHEMBL24682194 | 0.83 | TSPO (0.42) | MAPTTSPORAB9APDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222630-A | 2-acetamido-6-hydroxy-benzothiophene derivatives having antiviral activity | OTC制药公司(JSC) | 2023-12-12 | — | — | CN | disclosed |
| WO-2022173329-A1 | 2-ACETAMIDO-6-HYDROXY-BENZOTHIOPHENE DERIVATIVES WITH ANTIVIRAL ACTIVITY | Акционерное общество "Отисифарм" | 2022-08-18 | — | — | WO | disclosed |