Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29804499 | 1.00 | ALDH1A1 (0.43) | ALDH1A1ATMLMNAMALT1SCN10A | |
| SCHEMBL29109937 | 0.94 | LMNA (0.45) | ALDH1A1ATMLMNASCN10ARXFP1 | |
| SCHEMBL29804143 | 0.86 | MAPT (0.44) | ALDH1A1ATMMALT1SCN10ARXFP1 | |
| SCHEMBL24684269 | 0.86 | MAPT (0.44) | ALDH1A1ATMMALT1SCN10ARXFP1 | |
| SCHEMBL29804425 | 0.84 | ALDH1A1 (0.49) | ALDH1A1ATMLMNASCN10ARXFP1 | |
| SCHEMBL24682627 | 0.84 | ALDH1A1 (0.49) | ALDH1A1ATMLMNASCN10ARXFP1 | |
| SCHEMBL24682671 | 0.82 | PIK3CD (0.45) | ALDH1A1ATMLMNASCN10ASCN8A | |
| SCHEMBL29804274 | 0.82 | PIK3CD (0.45) | ALDH1A1ATMLMNASCN10ASCN8A | |
| SCHEMBL24682598 | 0.82 | LRRK2 (0.46) | ALDH1A1ATMLMNASCN10A | |
| SCHEMBL29804309 | 0.82 | LRRK2 (0.46) | ALDH1A1ATMLMNASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192487-A2 | METHYL-SUBSTITUTED PYRIDINE AND PYRIDAZINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE | LATIGO BIOTHERAPEUTICS, INC. (US) | 2022-09-15 | — | — | WO | disclosed |