Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | SCN1A | P35498 | 4/20 | 0.54 |
| ▸ | SCN2A | Q99250 | 4/20 | 0.54 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2469904 | 0.93 | LMNA (0.69) | LMNAKDM4EALDH1A1SCN1ASCN2A | |
| SCHEMBL12320510 | 0.85 | LMNA (0.56) | LMNAKDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL27537998 | 0.84 | LMNA (0.57) | LMNAKDM4EALDH1A1MAPTL3MBTL1 | |
| SCHEMBL11334557 | 0.83 | ALDH1A1 (0.66) | LMNAKDM4EALDH1A1SCN1ASCN2A | |
| SCHEMBL11401080 | 0.83 | SCN1A (0.67) | LMNAKDM4EALDH1A1SCN1ASCN2A | |
| SCHEMBL11345167 | 0.82 | SCN1A (0.65) | LMNAKDM4EALDH1A1SCN1ASCN2A | |
| Citric Acid SCHEMBL2469293 | 0.81 | KDM4E (0.58) | LMNAKDM4EALDH1A1SCN1ASCN2A | |
| SCHEMBL2590580 | 0.80 | SCN1A (0.67) | LMNAKDM4EALDH1A1SCN1ASCN2A | |
| SCHEMBL30059224 | 0.80 | SCN1A (0.67) | LMNAKDM4EALDH1A1SCN1ASCN2A | |
| SCHEMBL18224473 | 0.79 | HCRTR1 (0.57) | LMNAKDM4EALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111808011-B | High penetration composition and its application | 泰飞尔生物医药(苏州)有限公司 | 2024-02-27 | — | — | CN | disclosed |
| CN-107320732-B | High penetration composition and application thereof | 于崇曦 | 2021-09-07 | — | — | CN | disclosed |
| CN-108191846-B | High penetration composition and application thereof | 于崇曦 | 2021-08-20 | — | — | CN | disclosed |
| EP-2370406-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | Yu, Chongxi (US) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010065936-A1 | HIGH PENETRATION COMPOSITIONS AND THEIR APPLICATIONS | YU CHONGXI (US) | 2010-06-10 | — | — | WO | disclosed |