Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24687063 | 0.93 | ROCK2 (0.47) | ANO1MEN1KMT2ASMN1; SMN2P2RX4 | |
| SCHEMBL24687066 | 0.88 | MEN1 (0.40) | ANO1MEN1KMT2ASMN1; SMN2P2RX4 | |
| SCHEMBL24685918 | 0.86 | ANO1 (0.44) | ANO1MEN1KMT2ASMN1; SMN2P2RX4 | |
| SCHEMBL30629447 | 0.85 | P2RX4 (0.55) | ANO1P2RX4 | |
| SCHEMBL24685914 | 0.85 | P2RX4 (0.55) | ANO1P2RX4 | |
| SCHEMBL24686721 | 0.82 | P2RX4 (0.42) | ANO1MEN1KMT2ASMN1; SMN2P2RX4 | |
| SCHEMBL24687283 | 0.82 | ROCK2 (0.45) | ANO1MEN1KMT2AP2RX4ROCK2 | |
| SCHEMBL24686710 | 0.79 | P2RX4 (0.55) | P2RX4 | |
| SCHEMBL30629444 | 0.79 | P2RX4 (0.55) | P2RX4 | |
| SCHEMBL24687064 | 0.78 | MMP1 (0.46) | MEN1KMT2ASMN1; SMN2P2RX4MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |