Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24686722 | 0.88 | ANO1 (0.48) | MEN1KMT2ASMN1; SMN2ANO1NPC1 | |
| SCHEMBL24687062 | 0.84 | NPC1 (0.40) | MEN1KMT2ASMN1; SMN2NPC1MAPT | |
| SCHEMBL24687063 | 0.83 | ROCK2 (0.47) | MEN1KMT2ASMN1; SMN2ANO1MAPT | |
| SCHEMBL24685918 | 0.75 | ANO1 (0.44) | MEN1KMT2ASMN1; SMN2ANO1RECQL | |
| SCHEMBL30629447 | 0.74 | P2RX4 (0.55) | ANO1P2RX4 | |
| SCHEMBL24685914 | 0.74 | P2RX4 (0.55) | ANO1P2RX4 | |
| SCHEMBL24687073 | 0.74 | P2RX4 (0.51) | P2RX4KCNJ5KCNJ3 | |
| SCHEMBL24687283 | 0.72 | ROCK2 (0.45) | MEN1KMT2AANO1MAPTRECQL | |
| SCHEMBL24686435 | 0.71 | P2RX4 (0.64) | P2RX4 | |
| SCHEMBL29852261 | 0.71 | P2RX4 (0.64) | P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |