Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.47 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.46 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24686030 | 0.91 | ROCK2 (0.49) | ANO1P2RX4KCNJ5KCNJ3MEN1 | |
| SCHEMBL24685908 | 0.84 | KCNJ5 (0.61) | ANO1P2RX4KCNJ5KCNJ3MEN1 | |
| SCHEMBL24687088 | 0.81 | ROCK2 (0.49) | ANO1P2RX4KCNJ5KCNJ3MEN1 | |
| SCHEMBL24686422 | 0.81 | ANO1 (0.50) | ANO1P2RX4KCNJ5KCNJ3MEN1 | |
| SCHEMBL24686770 | 0.81 | ANO1 (0.48) | ANO1P2RX4KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL24685925 | 0.80 | ANO1 (0.52) | ANO1P2RX4KCNJ5KCNJ3MEN1 | |
| SCHEMBL24686358 | 0.79 | LMNA (0.44) | KCNJ5KCNJ3MEN1KMT2AALDH1A1 | |
| SCHEMBL24685940 | 0.79 | SMN1; SMN2 (0.58) | P2RX4MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL24687101 | 0.74 | MAPT (0.38) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL19576777 | 0.73 | P2RX4 (0.61) | P2RX4ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |