Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.44 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24686030 | 0.90 | ROCK2 (0.49) | ROCK2P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL24687034 | 0.85 | KCNJ5 (0.61) | P2RX4MEN1KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL24687090 | 0.84 | ADAMTS4 (0.51) | ROCK2P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL24686679 | 0.82 | RECQL (0.47) | ROCK2P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL24686769 | 0.81 | ANO1 (0.51) | ROCK2P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL19576777 | 0.81 | P2RX4 (0.61) | ROCK2P2RX4 | |
| SCHEMBL24687094 | 0.81 | ANO1 (0.52) | P2RX4MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL24687103 | 0.81 | RECQL (0.53) | ROCK2P2RX4P2RX7MEN1KMT2A | |
| SCHEMBL24686362 | 0.80 | SMN1; SMN2 (0.58) | P2RX4MEN1KMT2AMAPTLMNA | |
| SCHEMBL24687283 | 0.79 | ROCK2 (0.45) | ROCK2P2RX4P2RX7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |