Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 11/20 | 0.51 |
| ▸ | KCNJ5 | P48544 | 4/20 | 0.48 |
| ▸ | KCNJ3 | P48549 | 4/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24687283 | 0.90 | ROCK2 (0.45) | P2RX4KCNJ5KCNJ3ROCK2ALDH1A1 | |
| SCHEMBL24686674 | 0.88 | KCNJ5 (0.54) | P2RX4KCNJ5KCNJ3CLK2PRKX | |
| SCHEMBL24687083 | 0.88 | SMN1; SMN2 (0.54) | P2RX4ALDH1A1 | |
| SCHEMBL29852261 | 0.87 | P2RX4 (0.64) | P2RX4 | |
| SCHEMBL24686435 | 0.87 | P2RX4 (0.64) | P2RX4 | |
| SCHEMBL24686639 | 0.86 | KCNJ5 (0.55) | P2RX4KCNJ5KCNJ3CLK2PRKX | |
| SCHEMBL24685910 | 0.84 | KCNJ5 (0.50) | P2RX4KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL24686743 | 0.84 | KCNJ5 (0.48) | P2RX4KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL24687037 | 0.83 | RECQL (0.49) | P2RX4KCNJ5KCNJ3CLK2PRKX | |
| SCHEMBL24687074 | 0.82 | KCNJ5 (0.48) | P2RX4KCNJ5KCNJ3CLK2PRKX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |