Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24687073 | 0.88 | P2RX4 (0.51) | P2RX4ALDH1A1 | |
| SCHEMBL24685959 | 0.88 | P2RX4 (0.59) | SMN1; SMN2KMT2ATSHRNPSR1P2RX4 | |
| SCHEMBL30629443 | 0.88 | P2RX4 (0.59) | SMN1; SMN2KMT2ATSHRNPSR1P2RX4 | |
| SCHEMBL24685962 | 0.87 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ATSHRNPSR1P2RX4 | |
| SCHEMBL24687283 | 0.84 | ROCK2 (0.45) | KMT2AP2RX4MAPTMEN1ALDH1A1 | |
| SCHEMBL24685939 | 0.83 | SMN1; SMN2 (0.48) | SMN1; SMN2KMT2ATSHRNPSR1P2RX4 | |
| SCHEMBL24686362 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2ATSHRNPSR1P2RX4 | |
| SCHEMBL24685940 | 0.80 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2ATSHRNPSR1P2RX4 | |
| SCHEMBL24686058 | 0.76 | P2RX4 (0.63) | SMN1; SMN2P2RX4 | |
| SCHEMBL29852275 | 0.76 | P2RX4 (0.63) | SMN1; SMN2P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |