Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24685940 | 0.91 | SMN1; SMN2 (0.58) | SMN1; SMN2KMT2ATSHRNPSR1NPC1 | |
| SCHEMBL24687094 | 0.85 | ANO1 (0.52) | SMN1; SMN2KMT2ANPC1RAB9AP2RX4 | |
| SCHEMBL24687034 | 0.82 | KCNJ5 (0.61) | KMT2AP2RX4LMNAPOLBMEN1 | |
| SCHEMBL24686357 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2ATSHRNPSR1NPC1 | |
| SCHEMBL24687083 | 0.80 | SMN1; SMN2 (0.54) | SMN1; SMN2KMT2ATSHRNPSR1NPC1 | |
| SCHEMBL24687088 | 0.80 | ROCK2 (0.49) | SMN1; SMN2KMT2AP2RX4LMNAMAPT | |
| SCHEMBL18301837 | 0.76 | P2RX4 (0.69) | SMN1; SMN2KMT2ATSHRNPSR1NPC1 | |
| SCHEMBL24685925 | 0.75 | ANO1 (0.52) | SMN1; SMN2KMT2ANPC1RAB9AP2RX4 | |
| SCHEMBL24173209 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2ATSHRNPSR1NPC1 | |
| SCHEMBL24686622 | 0.73 | LMNA (0.43) | SMN1; SMN2KMT2ANPC1RAB9AP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |