Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24686674 | 0.92 | KCNJ5 (0.54) | P2RX4KCNJ5KCNJ3MAOB | |
| SCHEMBL24687283 | 0.90 | ROCK2 (0.45) | ADAMTS4MMP2MMP13MMP14ADAMTS5 | |
| SCHEMBL24687103 | 0.85 | RECQL (0.53) | ADAMTS4MMP2MMP13MMP14ADAMTS5 | |
| SCHEMBL29852110 | 0.85 | P2RX4 (0.60) | ADAMTS4MMP2MMP13MMP14ADAMTS5 | |
| SCHEMBL24686059 | 0.85 | P2RX4 (0.60) | ADAMTS4MMP2MMP13MMP14ADAMTS5 | |
| SCHEMBL24686724 | 0.84 | ADAMTS4 (0.46) | ADAMTS4MMP2MMP13MMP14ADAMTS5 | |
| SCHEMBL24687088 | 0.84 | ROCK2 (0.49) | P2RX4ROCK2P2RX7KMT2AMEN1 | |
| SCHEMBL24686030 | 0.84 | ROCK2 (0.49) | P2RX4ROCK2P2RX7KMT2AMEN1 | |
| SCHEMBL24686385 | 0.84 | RECQL (0.45) | ADAMTS4MMP2MMP13MMP14ADAMTS5 | |
| SCHEMBL24686639 | 0.83 | KCNJ5 (0.55) | P2RX4MAPTKCNJ5KCNJ3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161416-A1 | AROMATIC COMPOUND, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 武汉朗来科技发展有限公司 | 2022-08-04 | — | — | WO | disclosed |